Common names or abbreviations:
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CHD= Canine Hip
Dysplasia
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HD = Hip Dysplasia
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Description or definition:
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“Canine
hip dysplasia is a genetic disease of dogs that causes looseness, abnormal
development and arthritis of the hip joint. The hip joint is a
'ball-and-socket' type joint. The 'ball' is the uppermost part of the
thighbone, or femur, and is called the 'head of the femur. The 'head' is
connected to the rest of the bone by the 'neck'. The 'socket' is part of the
pelvic bone, and is called the 'acetabulum'. Normally, the ball, or head of
the femur, fits very tightly within its socket, or acetabulum. With hip
dysplasia, this fit becomes loose and the joint partially dislocates, or
subluxates. This subluxation can cause discomfort, abnormal development and
arthritis, later in life. Hip dysplasia is usually a bilateral disease,
which means both hips are often affected.
Canine
hip dysplasia is an extremely common disease today, despite over 25 years of
organized effort to reduce its incidence. Nearly one third of all orthopedic
cases, seen at referral institutions, have hip joint disease related to CHD.
According to the Orthopedic Foundation for Animals, the percentage of
pure-bred dogs with CHD ranges from 1.8% to 48.1%, depending on the breed.
Most commonly, CHD affects the large and giant breeds, although any breed
can be affected.
In
puppies, the looseness, or laxity, develops at around 4 months of age.
Laxity alone can cause soreness in some dogs, usually in puppies 6 - 10
months old. Since the head of the femur is not seated well in its socket,
the surrounding tissues are asked to provide more support than they are
capable of, especially during exercise. These tissues can stretch and tear
causing discomfort. Between the ages of 6 months - 2 years old, arthritis
begins and progresses for the life of the pet. Severe arthritis also causes
soreness, which usually occurs in the older dog who may have had problems as
a puppy or who never showed any previous signs at all. Arthritis is the
body's response to inflammation and hip laxity. The most notable changes
that occur are the progressive thickening of the tissues around the joint
and the production of bone around the head of the femur and acetabulum.
The
specific mechanisms which cause CHD are not known. Genetics certainly plays
a role, however, the specifics of how the disease is passed from one
generation to the next, is very-complex and not completely understood.
For
example, puppies born from a breeding pair with hip dysplasia, although more
likely to have the disease, may be completely normal. Similarly, normal
breeding pairs, although more likely to have normal puppies, may produce
offspring with severe hip dysplasia. This complexity with regard to genetics
has frustrated efforts to eliminate the disease completely, and has led
people to believe that environmental factors are responsible for disease
expression, as well.
Nutrition
and growth rate are considered to be important environmental factors related
to CHD. There is strong evidence, from a number of studies, that dogs who
are overfed, and gain weight too rapidly, are predisposed to CHD. This seems
to be most important for large or giant breeds in the first 6 months of
life. There is good evidence that puppies who grow more slowly have less
chance of acquiring CHD. The final adult body size of these puppies is about
the same as puppies who grow more quickly. Therefore, feeding premium
puppy-foods, 'free-choice' to puppies, is NOT recommended, especially with
large breed dogs. Additionally, providing vitamin or calcium supplements, is
NOT recommended for puppies who are fed a balanced nutritionally complete
dog food. Most reputable dog foods, even those for adult dogs, have all the
vitamins and minerals puppies need. Veterinarians, or veterinary
nutritionists, should be consulted when deciding how much of what food is
safe to feed the growing puppy.
Dogs
showing signs of soreness with CHD can be any age and any size. However,
most of the dogs are large, weighing from 45 - 90 pounds. Whether young or
old, the signs of CHD are similar. Most commonly, an owner will notice that
their pet is reluctant to exercise, work or play.
Common
complaints are:
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Limping or short-strided steps
in the rear legs
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Slow to get the rear-end up off
the floor, and slow to lie down.
·
Difficulty with climbing stairs
or jumping.
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Tends to 'warm out' of the
lameness (limping), which is worst when the pet first gets up, morning
stiffness.
·
Tends to be worse after heavy
exercise, usually the next day.
·
Some days are better than
others, often cold and wet days are worse.
These
signs of CHD rarely crop up, or worsen suddenly. Usually owners have
perceived a problem for a long time and have noticed the signs getting worse
slowly, over months or years. Additionally, the signs of CHD are rarely
severe. Dogs usually show only mild to moderate lameness or soreness.
Signs
of problems NOT consistent with CHD include:
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All of a sudden, there's a
problem with, the back legs, and there's never been a problem before.
·
There's been a mild problem for
a long time, but the signs are suddenly much worse.
·
He/she is holding the limb up,
completely off the floor.
·
He/she is having tremendous
trouble sitting up and walking, and sometimes can't get up at all.
If
any of these signs are present, the problem is NOT likely to be CHD. The
most common rear-end diseases, mistaken for CHD, are knee and back problems.
Knee problems usually cause the animal to hold the limb up off the ground,
which is rare with CHD. Back problems, like slipped discs, cause injury to
the spinal cord or nerves. Dogs with neurological disease of the back will
often walk uncoordinated in the rear-end, with a 'drunkard-type' gait.
Some
dogs will tend to scrape their feet or toe nails when walking. Both
incoordination and dragging the feet are NOT usually seen with CHD.
Many
different diseases can cause rear leg problems. Just because a dog has some
arthritis of the hips, does NOT mean that the problem is, related to CHD or
even the hips themselves. Determining the cause of rear leg problems is
often difficult and requires consultation with an experienced veterinarian
or orthopedic specialist.
Deciding
which tests to use when evaluating a dog for CHD depend significantly on the
patient's age. As mentioned, younger dogs with CHD, tend to have notable
laxity without much arthritis. Therefore, with younger dogs, the primary
goal toward diagnosing CHD is detecting hip joint laxity. Palpation, or
careful manipulation of the hip, is an extremely important tool. There are
certain manipulation tests that are very sensitive at identifying laxity of
the hip joint. Often the patient needs to be sedated, or anesthetized, in
order to permit careful and gentle manipulations. Radiographs (x-rays) can
also be very helpful when trying to identify laxity in the hip joint.
The
Older Dog (over 1 year of age)
As
mentioned, older dogs with CHD, tend to have arthritis, and less notable
laxity. In these older dogs, the primary goal toward diagnosing CHD is
detecting evidence of hip joint arthritis. Radiographs are the best method
and the routine view, with the legs pulled straight back, provides a
sensitive indicator for even the earliest signs of arthritis.” http://www.grr-tx.com/resources/hipdys_overview.htm
Whether
younger or older, the clinical consequences of CHD are extremely variable
from dog to dog. For example, some young dogs with laxity never develop
arthritis, and some old dogs with severe arthritis never show signs of
soreness.
Most
veterinary orthopedic surgeons agree that if signs of limping or soreness
are very mild, or absent, then treatment probably isn't necessary. Some
owners worry about their pet being sore, yet not showing any signs. It is
true that some dogs are more stoic than others, like people. But most dogs
that are significantly uncomfortable, even the toughest, will show one or
more of the signs listed earlier. In general, a dog with CHD that performs
well, and can run, jump and play normally, probably does NOT need treatment.
Some
owners, may request a surgical treatment because they would rather do the
surgery on their pet when it is young and healthy, than later when the pet
is older. Most of the surgeries are safely and routinely done on older pets.
The modern anesthetic drugs are extremely safe, and anesthetic complications
occur very rarely. Additionally, most of the surgeries, especially for the
older dogs, do not become more difficult to perform with time, and some
actually get easier. Remember, if your dog is not showing signs, there's no
need to put him/her through a surgery now, that he/she may never need in the
future.
Conservative
therapy can be a good option for many dogs, especially the younger ones, who
may do well for years once they get over their first bouts of soreness.
Weight
control is extremely important. Obesity causes excessively high forces to be
transmitted through already abnormal hips. Soreness may be exacerbated, and
arthritis accelerated, in dogs that are overweight. The appropriate weight
and diet program for your dog can be obtained from your veterinarian or from
a veterinary nutritionist.
Anti-inflammatory
medication is an important part of conservative therapy especially when
soreness flares up. Aspirin is the most commonly used drug, however there
are other oral medications or injections that can be very effective. Consult
your veterinarian, or veterinary orthopedic-specialist, for the appropriate
doses, medications and prescriptions. DO NOT treat your dog yourself.
Drugs
such as aspirin, acetaminophen (Tylenol) and ibuprofen (Advil, Motrin) can
be extremely toxic to dogs when given an incorrect dose. The metabolism and
dosages of some drugs are much different in dogs as compared to people.
Exercise
must be controlled for conservative therapy to be effective. "Full-out" running, jumping and roughhousing should be prohibited
as much as possible. Extended walks or jogs, on a leash, can be beneficial.
When soreness flares up, exercise should be extremely limited for a few
days. Often cage or kennel rest works best. Some owners mistakenly believe
that their pet knows his or her own limits, and will restrict themselves as
needed. In general this is not true. It could be argued that many people
don't recognize their own limits, and will 'over-do-it' exercising, even
though they're likely to regret it the next day. Most dogs are like these
people. If allowed, they will run, jump or play to their fullest ability,
even though they are likely to reinjure themselves. Owners must take
responsibility for limiting the exercise for their pets.
The
three most common surgical treatments of CHD have three differing
objectives. One objective is to save the dog's own natural joint by
eliminating the laxity and preventing the progression of arthritis. This
objective is usually reserved for the younger dogs who still have a joint
worth saving. A second objective is to remove the source of the soreness by
removing part of the joint itself. The arthritic femoral head and neck are
removed and a 'false-joint' made of scar tissue and muscle eventually
provides, relatively, pain-free movement. The third and final objective is
to remove and replace the arthritic femoral head and acetabulum with an
artificial joint. With joint replacement, dogs maintain normal movement and
mechanics of the hip joint, and are pain-free very soon after surgery.
Triple
pelvic osteotomy (TPO) is a surgery designed to save the natural joint by
reducing or eliminating the laxity, or looseness. If the laxity is
eliminated then the arthritis, which would follow, can be prevented. With
TPO, the pelvis is cut in three places ('triple osteotomy' means 'three cuts
in bone'), so the acetabulum, or socket, can be rotated over the head of the
femur to prevent it from slipping out of the socket or subluxating.
The
TPO is not appropriate for all dogs and works best in dogs that have no
arthritis present in their hips. Dogs are usually younger (5-10 months old)
when this surgery is performed, before arthritis has begun. Usually both
hips are operated in two separate surgeries, 4 - 8 weeks apart. Most
surgeons reserve this surgery for dogs that are significantly sore, and
showing many, or all, of the signs consistent with CHD described earlier.
Exercise must be severely restricted, for 2 - 3 months, to allow the pelvic
bones to heat after surgery.
The
TPO surgery has a good success rate if it is performed on an appropriate
candidate; many dogs are improved clinically and arthritis is effectively
prevented in some dogs.
Femoral
Head and Neck Ostectomy (FHO) is designed to eliminate the source of
discomfort by removing part of the hip joint. The femur is cut so that the
head and neck of the femur are removed ('ostectomy' means' bone is cut and
removed'). Scar tissue forms between the femur and acetabulum, where the
femoral head and neck used to be; this is called a 'false-joint' because
motion, between, the bones, is maintained without the 'true' ball-and-socket
joint. Eventually, this scar tissue provides enough support to permit use of
the limb without causing significant discomfort.
The
FHO surgery is usually performed on older dogs, which already have
significant arthritis. Usually one hip is operated on at a time, although
some surgeons prefer to do both hips at the same time. One major advantage
of the FHO is that exercise restriction is only needed for a few days after
the surgery. After 10 - 14 days, exercise is even encouraged to accelerate
formation of scar tissue.
The
FHO surgery has a variable success rate. It can take up to 3 months for the
dog to start using the leg well. Additionally, almost one-third of owners
report that their dogs continue to limp or have trouble jumping, and 50% of
owners report muscle atrophy (thinning) in the leg that was operated. Many
surgeons feel that large or giant breeds do more poorly than smaller breeds,
with FHO.
Total
hip replacement (THR) is designed to eliminate the source of discomfort by
replacing the arthritic joint with an artificial joint or hip prosthesis.
The THR surgery is a state-of-the art procedure, very similar to the
operation in humans. The arthritic femoral head and neck is removed and
replaced with a metal head and stem (head- cobalt chrome metal; stem-
titanium metal). The arthritic socket is removed and replaced with a plastic
cup (high molecular-weight plastic). The metal head and plastic cup fit
together like the original ball-and-socket joint, providing support and
pain-free, mechanically sound movement almost immediately after surgery.
The
THR surgery is performed on dogs 9 months of age or older, which have
arthritis. Only one hip is operated on at a time, because most dogs will
only ever need one hip replaced. The smallest-sized implants are often too
large for dogs under 30 pounds. Exercise restriction must be enforced for 2
months, following the surgery, to allow all the tissues to heal around the
prosthesis.
Total
hip replacements have been performed in canine patients since 1974, and have
enjoyed excellent results. Over 95% of patients return to normal function
after the surgery. Over 80% of dogs-do NOT need a second surgery despite the
presence of arthritis in the other hip. Animals will run, jump and play as
they did before the discomfort hindered them. Working animals, including
police and hunting dogs, have successfully returned to their duties after
THR.
Other
surgeries have been reported as beneficial in the treatment of CHD. These
surgeries, designed to reduce soreness and eliminate the laxity associated
with CHD, include Intertrochanteric osteotomy (ITO) and pectineal myectomy.
Although there may be occasional indications for these procedures, nether
has been shown to reliably prevent the progression of arthritis. Therefore,
any improvement noted post-operatively with these procedures, may be
short-lived.
Canine
hip dysplasia is a common disease, however, many diseases can mimic it's
signs and complicate diagnosis. Canine hip dysplasia is also a complex
disease with numerous treatment alternatives. Deciding which treatment is
best for your dog depends on numerous factors, including: severity of the
signs, the dog's age, your pets purpose in life (i.e., pet, hunting or
police) and financial concerns. The surgical procedures, if needed, are
difficult to perform and often require the services of surgeons with
advanced training. If you have questions about CHD, your first step should
be to call or schedule an appointment with your local veterinarian. If
additional help is needed, your veterinarian can schedule a consultation
with the nearest veterinary orthopedic specialist.
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Glossary
Acetabulum-
The socket component of the hip joint, and part of the pelvis.
Arthritis-
a chronic degenerative condition of the joint which can cause pain and is
usually associated with added bone around the joint.
Atrophy-
a wasting, or loss of mass, especially muscle.
Bilateral-
on both sides, left and right.
Congenital-
present at birth.
Dysplasia-
abnormal development of a body part.
Dysplastic-
having canine hip dysplasia.
Femoral-
relating to the Femur.
Femur-
the thigh bone.
Lameness-
abnormality in gait, limping.
Laxity-
looseness, usually related to a joint.
Luxation-
when a joint is completely out of place, or dislocated.
Ostectomy-
a cutting and removing of bone.
Osteotomy-
a cutting of bone, as with a saw.
Pelvic-
relating to the pelvis.
Pelvis-
the basin-like skeletal structure that connects the spinal column to the hind
limbs.
Prosthesis-
an artificial device used to replace a missing body part.
Radiographs-
x-rays
Subluxation-
when a joint is partially out of place, or partially dislocated.
Non-traditional treatments (not validated by controlled trials):
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acupuncture
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chiropractic
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vitamin therapy (generally
Vitamins C & E & selenium)
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superoxide dismutase
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Medical therapy (aimed at reducing pain/inflammation from
arthritic changes):
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aspirin
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bute
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adequan therapy
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"Adequan is a polysulfated
glycosaminoglycan which is used primarily for treatment of degenerative joint
disease in horses. In fact, it is not actually approved in the U.S. for dogs.
However, I have seen remarkable results in many of my older patients with
chronic DJD. In theory, it stimulates increased production of joint fluid and
the joint moves more freely and with less pain. It does not always work, but
when it does, it is usually dramatic." -Ralph M. Askren, DVM
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Gycoflex, Cosequin (a
synthetic glycosaminoglycans supplement) glucosamin -- similar effects to
Adequan
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Rimadyl -- a new non-steriod
anti-inflammatory drug, can help considerably in some cases without the
typical side effects of traditional steroidal drugs.
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EDITORS NOTE *CAUTION: MANY NEGATIVE SIDE EFFECTS
HAVE BEEN DOCUMENTED ON RIMADYL. PLEASE
DO NOT USE RIMADYL OR ANY OTHER NON –STEROIDAL ANTI INFLAMMATORY DRUG (NSAID)
WITHOUT KNOWING ALL OF ITS PROS AND CONS
EtoGesic is approved for osteoarthritis (1998) in dogs. It
is a non-steroidal anti-inflammatory drug and appears to avoid the liver
problems sometimes associated with Rimadyl.
*AGAIN, MANY PEOPLE DO NOT RECOMMEND USING NSAID.
DO NOT PUT YOUR DOG ON ANY DRUG WITHOUT INVESTIGATING FURTHER.*

Normal Hip Joint

Bad Hips

Total
Hip Replacement
Links to sites about this disease:
Treatment / Management
Cart Pulling exercise
“A
newer medical approach to the treatment of degenerative arthritis secondary
to
hip dysplasia involves the use of products called polysulfated
glycosaminoglycans or
PSGAGs. PSGAGs are naturally occurring components of the joint cartilage and
increase
joint fluid production. Although results are preliminary and no controlled
studies in dogs
have been performed, there have been several reported successes with these
compounds
in selected cases.”
Lew Olson LMSW-ACP PhD Natural Health writes:
“Cosequin is a blend of glucosamine and chondroitin sulfate. I have asimilar
blend that also has the manganese which is so important for the uptake of these
two ingredients to the joints, and my Bertes Flexile Plus is about 1/3 to 1/2
the price of cosequin. The Bertes Flexile Plus is also human grade
ingredients... I had it designed for my 87 old father three years ago... now I
take it too, plus too of my older dogs.
This traditional surgery involves replacing the femoral
head or ball portion of the joing with a metal prosthesis. The acetabulum is
replaced with a polyethylene socket. The procedure thus removes the source of
pain and inflammation as the bone is no longer in contact with the degenerated
joint.
Cemented vs. Uncemented Hip Replacements:
Uncemented hip prosthesis (subcategory of hip replacement
surgery)
Dr. David J. DeYoung of NCSU, professor of orthopedic surgery in the College of
Veterinary Medicine, helped develop the prosthesis based on a human version that
is held in place without cement. The prosthesis features a beaded surface into
which bone and fibrous tissue can grow and secure the components. More than 100
of the new prostheses have been implanted in dogs over a five-year period
without loosening or infection, two of the main concerns with cemented total hip
replacements…
This summary provided by:
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Michelle O'Bough
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